Circrna-hosting gene

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August undefined, 2024

WebJan 24, 2024 · A Kyoto Encyclopedia of Genes and Genomes analysis indicated that the differentially expressed circRNA-hosting genes were significantly enriched in the plant–pathogen interaction pathway, including 15 S genes (gene with significantly differential expression was annotated in special database). WebNov 9, 2015 · We tested circRNA candidates that were present in at least 6 out of 18 samples with at least 5 junction spanning reads for divergent expression to the host gene. From the initial 116 circRNA candidates, 72 of the circRNAs were significant (P-value ≤ 0.05 after correction for multiple testing, see Supplementary Table S4).

GreenCircRNA: a database for plant circRNAs that act as miRNA …

WebResults: We found that circRNAs has average higher expression over its host linear genes in peripheral blood. Compared to adjacent normal tissues, circSMARCA5 is decreased in breast cancer tissues, contrary to host gene SMARCA5. The enforced expression of circSMARCA5 induced drug sensitivity of breast cancer cell lines in vitro and in vivo. WebMay 28, 2024 · To identify the role of circRNA in the host and viral interactions, researchers have developed competing endogenous RNA (ceRNA) networks to explore circRNA … philips headphones shp2600

riboCIRC: a comprehensive database of translatable circRNAs

WebDec 14, 2024 · Abstract. Circular RNAs (CircRNAs) are single-stranded, covalently closed RNA molecules that are ubiquitous across species ranging from viruses to … WebGene Length: The host genes of circRNA-producing genes are, on average, longer and contain more splice sites than other genes . We therefore compared the length of the … WebMay 14, 2024 · Gene Ontology (GO) analysis of the circRNA host genes revealed an enrichment for epigenetic functions including histone modification (q-val: 5.52 ×10 −6), histone H3-K36 methylation (q-val: 8. ... philips headphones shp8900

CircRNA inhibits DNA damage repair by interacting with …

The RNA-binding protein SFPQ preserves long-intron splicing and …

WebAug 13, 2024 · analysis methods to clarify the relationship between circRNA and its host gene. Besides, genetic or epigenetic factors contributing to circRNA regulation have not been fully explored in cancers. WebFeb 25, 2015 · A circRNA that was markedly downregulated at later stages arose from the host gene coding for Rmst, thereby supporting a potential function of circRNAs in brain development. philips headphones shp9600Web2 days ago · Moreover, the enrichment analysis of DE circRNA host genes showed that they were mainly involved in muscle contraction, muscle organ development and muscle system processes, as well as AMPK and cAMP-related signal pathways. ... Previous studies have shown that circRNAs could regulate host gene transcription by competing with … trutholbyeva

"WebDec 4, 2024 · CircRNAs are relatively poorly studied members of the non-coding RNA family. These unique single-stranded molecules are generated through back-splicing of pre-mRNAs in a wide range of eukaryotic and prokaryotic taxa ( Danan et al., 2012; Holdt, Kohlmaier & Teupser, 2024 ), and even viruses ( Huang et al., 2024 ). " - Circrna-hosting gene

Circrna-hosting gene

Identification of circular RNAs with host gene-independent ... - PubMed

WebJun 1, 2024 · Circular RNAs (circRNAs) are involved in various biological processes and disease pathogenesis. However, only a small number of functional circRNAs have been identified among hundreds of thousands of circRNA species, partly because most current methods are based on circular junction counts and overlook the fact that a circRNA is … WebJun 28, 2024 · circBank采用 host gene+阿拉伯数字的形式，如：hsa_circEGFR_001。具体规则如下图所示： circBank规定，来源于同一个宿主基因的circRNA其名字前半部分的“hsa_circA”保持不变，仅以最后的阿拉伯数字以示区分，转录起始位点越靠前，阿拉伯数字越小，如图中所示的circA_001和circA_004。对于有相同转录起始位点的circRNA，其 …

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WebTo further study the function of the host genes, which were significantly enriched in immune-related pathways, the host gene-pathway-circRNA interaction network was constructed (Figure 7a), which contained 39 DEcircRNAs, 39 host genes, 7 immune-related significantly enriched pathways, and 206 interactions. WebIn this study, we constructed a novel circRNA–miRNA–mRNA network and further established a prognostic risk model consisting of four genes based on the ceRNA network to predict clinical outcomes of OSA patients. Based on the datasets, four candidate DEcircRNAs, hsa_circ_0035554 host gene, hsa_circ_0009034, hsa_circ_0007440, and …

WebFeb 11, 2024 · circRNAs Regulate Host Gene Expression as miRNA Sponges. circRNAs contain miRNA response elements (MREs) which bind to miRNAs and restrain their … WebApr 5, 2024 · To identify circRNA host genes, the program was provided with Ensembl 99 gene annotation 66. For each back-splicing event found, CIRI2 reports the number of reads mapping to the back-splicing ...

WebApr 14, 2024 · We found that while all genes producing circRNAs share gene architecture features common to circRNA host genes, genes producing circRNAs in PARP1 knockdown conditions had longer upstream introns than downstream introns, whereas flanking introns in wild type host genes were symmetrical. WebJun 17, 2016 · While the circRNA/hosting gene transcripts ratio is on average approximately 10 %, some circRNAs are expressed at levels even higher than their …

WebCircRNAs are dynamically expressed in a hiPSC-CM model of cardiac development and stress response. Some circRNAs show similar, host-gene independent expression dynamics in patient samples and may interact with the ribosome and RISC complex. In summary, the hiPSC-CM model uncovered a new signature of …

WebJun 8, 2024 · The schematic consists of two parts: one is a line of the host gene of the circRNA, with the exons and introns in the gene labeled; the other is a circle of the circular structure of circRNA, which is marked with corresponding colors that are the same as the position on the gene. trutholbyeva tierWebMar 8, 2024 · Circular RNAs (circRNAs) are an abundant class of covalently closed endogenous RNA molecules generated by back-splicing of pre-mRNAs. Recent … philips headphones taph805WebAug 24, 2024 · Deregulated circular RNAs (circRNAs) are associated with the development of cancer and therapy resistance. However, functional research of circRNAs mostly focus … philips headphones shs5200 reviewWebThe set of circular RNA host genes is enriched for chromatin modifiers and GTPase activity regulators. RNA-seq and qRT-PCR data showed that circular RNA expression … truth old style crossword clueWebApr 7, 2024 · A The intergenic circRNA Tae_circRNA00584 predicted acting as decoy of miRNA that sequester miRNAs away from their mRNAs. B The exonic-intron circRNA … philips headphones shs3200WebMar 21, 2024 · CircCHEK2, an editing-dependent ARcirc generated by back-splicing between exon 3 and 9 of its host gene CHEK2 (Fig. 3a), was chosen as an exemplary target for further study. philips headphones sound muffledWebJan 21, 2024 · Circular RNAs (circRNAs) represent an abundant and conserved entity of non-coding RNAs; however, the principles of biogenesis are currently not fully understood. Here, we identify two factors, splicing factor proline/glutamine rich (SFPQ) and non-POU domain-containing octamer-binding protein (NONO), to be enriched around circRNA loci. philips head screwdriver has cross shaped