WebRecombinant Human Cytohesin 3 protein is an Escherichia coli Full length protein 1 to 399 aa range, > 90% purity and validated in SDS-PAGE. WebCytohesin-3 antibody; General receptor of phosphoinositides 1 antibody; Grp1 antibody; PH antibody; PH, SEC7 and coiled-coil domain-containing protein 3 antibody; Protein …
Blocking the cytohesin-2/ARF1 axis by SecinH3 ... - ScienceDirect
WebAug 12, 2013 · The crystal structure of a cytohesin-3 construct encompassing the allosteric site in complex with the head group of phosphatidyl inositol 3,4,5-trisphosphate and N-terminally truncated Arf6-GTP reveals a large conformational rearrangement, whereby autoinhibition can be relieved by competitive sequestration of the autoinhibitory elements … WebJan 25, 2024 · Cytohesin-1 and cytohesin-2 are GEFs specific for Arf6 and are around 400 amino acids in length. Both proteins show high amino acid sequence similarities and are composed of four domains: an N-terminal helical domain, a catalytic Sec7 domain, a pleckstrin homology (PH) domain, and a C-terminal polybasic region ( 10, 12 ). chiming antonym
Anti-Cytohesin 3 antibody (ab155691) Abcam
WebJul 1, 2011 · Cytohesin-1 is a guanine nucleotide exchange factor for ADP ribosylation factor 6 (Arf6) in human blood neutrophils and differentiated PLB-985 neutrophil-like cells. Cytohesin-1 regulates adhesion and the transendothelial migration of monocytes, dendritic cells and T lymphocytes through activation of the β2 integrin LFA-1. In this study we … WebMay 3, 2024 · The cytohesin proteins, consisting of four closely related members (cytohesins-1, -2, -3, and -4), are a subfamily of the Sec7 domain-containing guanine nucleotide exchange factors for ADP ribosylation factors (Arfs), which are critical regulators of membrane trafficking and actin cytoskeleton remodeling. WebCytohesin-3 was upregulated in hepatocellular carcinoma tissues, correlating with overall survival/relapse-free survival and tumor size/vascular invasion. The PH domains of … chiminey cropmantis