Pisces protein activity
WebbPasquale Laise's 18 research works with 946 citations and 1,469 reads, including: Abstract B002: ARNTL2 is a Kras-dependent master regulator of hypoxic response in pancreatic ductal adenocarcinoma Webb20 juli 2024 · GitHub - Aleksobrad/single-cell-rcc-pipeline: Data files and code for analysis of single-cell ccRCC data for the manuscript "Tumor-Specific Cell Populations in Clear Cell Renal Carcinoma Associated with Clinical Outcome Identified Using Single-Cell Protein Activity Inference." Includes code for VIPER protein activity inference pipeline
Pisces protein activity
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Webb3 jan. 2024 · Proteins act through their interactions with other molecules. Catalytic proteins (enzymes) interact with substrate molecules; these interactions lower the activation energy of the reaction's rate limiting step, leading to an increase in the overall reaction rate. At the same time, cells and organisms are not static. Webb11 apr. 2024 · Background: Insulin resistance (IR) is a major contributing factor to the pathogenesis of metabolic syndrome and type 2 diabetes mellitus (T2D). Adipocyte metabolism is known to play a crucial role in IR. Therefore, the aims of this study were to identify metabolism-related proteins that could be used as potential biomarkers of IR …
Webb4 dec. 2008 · Detection of catalytic sites: performance of our scoring function. Our scoring function combined three characteristics of a given residue: the number of residues in contact with it through side-chain atoms (Dg 1 SC), the number of residues located at a path-length of three (Dg 3) and the type of the residue (Equation 1).It was used to detect … Webb11 jan. 2024 · In califano-lab/PISCES: Protein Activity Inferecne in Single Cells View source: R/viper_funcs.R PISCESViper R Documentation Runs VIPER on a seurat.obj that …
Webb12 aug. 2003 · Summary: PISCES is a public server for culling sets of protein sequences from the Protein Data Bank (PDB) by sequence identity and structural quality criteria. … Webb1 juni 2024 · PISCES leverages the assembly of lineage-specific gene regulatory networks, to accurately measure activity of each protein based on the expression its transcriptional targets (regulon), using the ARACNe and metaVIPER algorithms, respectively.
WebbPISCES is a R library. PISCES has no bugs, it has no vulnerabilities and it has low support. You can download it from GitHub. The pipeline for Protein Activity Inference in Single …
Webb10 juni 2024 · #### PISCES - Protein Activity Inference in Single-Cells - is a pipeline designed to apply the master regulator paradigm to single-cell datasets. This vignette … our lady of light prayerWebbGenerates protein activity readout using the NaRnEA... PISCESViper: Runs VIPER on a seurat.obj that has the appropriately... qc_filt: Filters raw gene expression data based on … our lady of lincoln catholic primaryWebbIn this study the ability of CF3 groups to bind electron rich side chains and backbone groups from proteins has been investigated by combining a Protein Data Bank (PDB) survey and ab initio quantum mechanics calculations. More precisely, an inspection of the PDB involving organic ligands containing a CF3 gro our lady of lichen polandWebbAndrea Califano Gene sets are being increasingly leveraged to make high-level biological inferences from transcriptomic data; however, existing gene set analysis methods rely on overly... our lady of limerickWebb11 jan. 2024 · Protein Activity Inferecne in Single Cells. Package index. Search the califano-lab/PISCES package. Vignettes. README.md Functions. 147. Source code. 15. Man ... In … roger page cricketWebb11 jan. 2024 · PISCES is the Califano lab pipeline for single-cell RNAseq analysis. It leverages the ARACNe-3 and NaRnEA algorithms to infer regulatory networks and … our lady of lebanon maronite church dcWebb25 jan. 2024 · PISCES leverages the assembly of lineage-specific gene regulatory networks, to accurately measure activity of each protein based on the expression its … our lady of light thrift store